Alina Chan
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Alina Chan is a Canadian
molecular biologist Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physi ...
specializing in
gene therapy Gene therapy is a medical field which focuses on the genetic modification of cells to produce a therapeutic effect or the treatment of disease by repairing or reconstructing defective genetic material. The first attempt at modifying human DN ...
and
cell engineering Cell engineering is the purposeful process of adding, deleting, or modifying genetic sequences in living cells to achieve biological engineering goals such as altering cell production, changing cell growth and proliferation requirements, adding or ...
at the
Broad Institute of MIT and Harvard Broad(s) or The Broad(s) may refer to: People * A slang term for a woman. * Broad (surname), a surname Places * Broad Peak, on the border between Pakistan and China, the 12th highest mountain on Earth * The Broads, a network of mostly navi ...
, where she is a
postdoctoral fellow A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to p ...
. During the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
she became known for questioning the prevailing consensus regarding the origins of the virus and publicly advocating a laboratory escape hypothesis.


Biography

Chan was born in
Vancouver, British Columbia Vancouver ( ) is a major city in western Canada, located in the Lower Mainland region of British Columbia. As the List of cities in British Columbia, most populous city in the province, the 2021 Canadian census recorded 662,248 people in the ...
, to
Singaporean Singaporeans, or the Singaporean people, refers to citizens or people who identify with the sovereign island city-state of Singapore. Singapore is a multi-ethnic, multi-cultural and multi-lingual country. Singaporeans of Chinese, Malay, India ...
parents. Her family returned to Singapore shortly after, where she grew up. She returned to Canada after high school to study
biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...
and
molecular biology Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physi ...
at the
University of British Columbia The University of British Columbia (UBC) is a public university, public research university with campuses near Vancouver and in Kelowna, British Columbia. Established in 1908, it is British Columbia's oldest university. The university ranks a ...
, where she earned a PhD. She then joined Harvard University as a postdoctoral scholar, later joining the Stanley Center for Psychiatric Research at the
Broad Institute The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: , pronunciation respelling: ), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, Cambridge, Massachusetts, U ...
.


COVID-19 origins

Chan became known during the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
for co-authoring a
preprint In academic publishing, a preprint is a version of a scholarly or scientific paper that precedes formal peer review and publication in a peer-reviewed scholarly or scientific journal. The preprint may be available, often as a non-typeset versio ...
according to which the virus was "pre-adapted" to humans and suggesting COVID-19 could have escaped from a laboratory. The preprint has not been accepted for publication by a
scientific journal In academic publishing, a scientific journal is a periodical publication intended to further the progress of science, usually by reporting new research. Content Articles in scientific journals are mostly written by active scientists such as s ...
, but received a significant reception in the
popular press Mass media refers to a diverse array of media technologies that reach a large audience via mass communication. The technologies through which this communication takes place include a variety of outlets. Broadcast media transmit information ...
. The reaction of virologists and other specialists to Chan's hypothesis has been largely, but not exclusively, negative. The ''New York Times'' noted in October 2021 that Chan's view has been "widely disputed by other scientists", but some have commended her willingness to advance alternative hypotheses in the face of controversy.
Jonathan Eisen Jonathan Andrew Eisen (born August 31, 1968) is an American evolutionary biologist, currently working at University of California, Davis. His academic research is in the fields of evolutionary biology, genomics and microbiology and he is the ac ...
of UC Davis praised Chan for raising the lab-origin discussion, but said her views remain conjecture, as not enough
disease outbreak In epidemiology, an outbreak is a sudden increase in occurrences of a disease when cases are in excess of normal expectancy for the location or season. It may affect a small and localized group or impact upon thousands of people across an entire ...
s have been traced in enough molecular detail to know what is normal, noting also that the virus continues to change and adapt. Sixteen months after Chan's preprint was shared online, a scientific review article published in ''
Cell Cell most often refers to: * Cell (biology), the functional basic unit of life Cell may also refer to: Locations * Monastic cell, a small room, hut, or cave in which a religious recluse lives, alternatively the small precursor of a monastery ...
'' described the pre-adaptation theory as "without validity." Chan detailed her views publicly in long
Twitter Twitter is an online social media and social networking service owned and operated by American company Twitter, Inc., on which users post and interact with 280-character-long messages known as "tweets". Registered users can post, like, and ...
postings called "tweetorials" and wrote opinion pieces on the subject with science journalist
Matt Ridley Matthew White Ridley, 5th Viscount Ridley, (born 7 February 1958), is a British science writer, journalist and businessman. He is known for his writings on science, the environment, and economics and has been a regular contributor to ''Th ...
in the ''
Wall Street Journal ''The Wall Street Journal'' is an American business-focused, international daily newspaper based in New York City, with international editions also available in Chinese and Japanese. The ''Journal'', along with its Asian editions, is published ...
'' and in ''
The Daily Telegraph ''The Daily Telegraph'', known online and elsewhere as ''The Telegraph'', is a national British daily broadsheet newspaper published in London by Telegraph Media Group and distributed across the United Kingdom and internationally. It was fo ...
''. Chan later signed open letters together with other scientists published in the ''
Wall Street Journal ''The Wall Street Journal'' is an American business-focused, international daily newspaper based in New York City, with international editions also available in Chinese and Japanese. The ''Journal'', along with its Asian editions, is published ...
'' and ''
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...
'', calling for full and unrestricted international forensic investigations into all possible origins of the virus. She was one of 18 scientists who signed a letter in ''
Science Magazine ''Science'', also widely referred to as ''Science Magazine'', is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, ...
'' calling again for a credible investigation into the origins of the virus. The letter called for a "proper investigation" into "both natural and laboratory spillovers" and was widely covered in the press and brought the debate on the possible lab origins of the virus into the mainstream. Chan and Ridley authored a book entitled '' Viral: The Search for the Origin of COVID-19'', published by HarperCollins in November 2021. Chan has stated after the book was published she planned to change her name. In September 2021, Chan participated in a debate on COVID-19 origins organized by ''
Science magazine ''Science'', also widely referred to as ''Science Magazine'', is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, ...
'', which included scientists Linfa Wang, Michael Worobey, and Jesse Bloom.


References


External links

* * {{DEFAULTSORT:Chan, Alina 21st-century Canadian biologists 21st-century Canadian women scientists Canadian molecular biologists Canadian people of Chinese descent Canadian people of Singaporean descent Canadian women biologists Living people Scientists from Vancouver University of British Columbia alumni Women molecular biologists Year of birth missing (living people)